Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

OBJECTIVE: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. RESULTS: A positive PCR result for HPV was observed in 121 cervical samples. A h...

Descripción completa

Detalles Bibliográficos
Autores principales: Ponce-Benavente, Luis, Rejas-Pinelo, Patricia, Aguilar-luis, Miguel Angel, Palomares-Reyes, Carlos, Becerra-Goicochea, Lorena, Pinillos-Vilca, Luis, Silva-Caso, Wilmer, Costa, Luis E., Weilg, Pablo, Alvitrez-Arana, Juan, Bazán-Mayra, Jorge, del Valle-Mendoza, Juana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069864/
https://www.ncbi.nlm.nih.gov/pubmed/30064521
http://dx.doi.org/10.1186/s13104-018-3644-7
Descripción
Sumario:OBJECTIVE: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. RESULTS: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3644-7) contains supplementary material, which is available to authorized users.

Ejemplares similares