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Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru

OBJECTIVE: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. RESULTS: A positive PCR result for HPV was observed in 121 cervical samples. A h...

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Autores principales: Ponce-Benavente, Luis, Rejas-Pinelo, Patricia, Aguilar-luis, Miguel Angel, Palomares-Reyes, Carlos, Becerra-Goicochea, Lorena, Pinillos-Vilca, Luis, Silva-Caso, Wilmer, Costa, Luis E., Weilg, Pablo, Alvitrez-Arana, Juan, Bazán-Mayra, Jorge, del Valle-Mendoza, Juana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069864/
https://www.ncbi.nlm.nih.gov/pubmed/30064521
http://dx.doi.org/10.1186/s13104-018-3644-7
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author Ponce-Benavente, Luis
Rejas-Pinelo, Patricia
Aguilar-luis, Miguel Angel
Palomares-Reyes, Carlos
Becerra-Goicochea, Lorena
Pinillos-Vilca, Luis
Silva-Caso, Wilmer
Costa, Luis E.
Weilg, Pablo
Alvitrez-Arana, Juan
Bazán-Mayra, Jorge
del Valle-Mendoza, Juana
author_facet Ponce-Benavente, Luis
Rejas-Pinelo, Patricia
Aguilar-luis, Miguel Angel
Palomares-Reyes, Carlos
Becerra-Goicochea, Lorena
Pinillos-Vilca, Luis
Silva-Caso, Wilmer
Costa, Luis E.
Weilg, Pablo
Alvitrez-Arana, Juan
Bazán-Mayra, Jorge
del Valle-Mendoza, Juana
author_sort Ponce-Benavente, Luis
collection PubMed
description OBJECTIVE: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. RESULTS: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3644-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-60698642018-08-06 Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru Ponce-Benavente, Luis Rejas-Pinelo, Patricia Aguilar-luis, Miguel Angel Palomares-Reyes, Carlos Becerra-Goicochea, Lorena Pinillos-Vilca, Luis Silva-Caso, Wilmer Costa, Luis E. Weilg, Pablo Alvitrez-Arana, Juan Bazán-Mayra, Jorge del Valle-Mendoza, Juana BMC Res Notes Research Note OBJECTIVE: Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient center in the Hospital Regional Docente de Cajamarca from March to September 2017. RESULTS: A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3644-7) contains supplementary material, which is available to authorized users. BioMed Central 2018-07-31 /pmc/articles/PMC6069864/ /pubmed/30064521 http://dx.doi.org/10.1186/s13104-018-3644-7 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Ponce-Benavente, Luis
Rejas-Pinelo, Patricia
Aguilar-luis, Miguel Angel
Palomares-Reyes, Carlos
Becerra-Goicochea, Lorena
Pinillos-Vilca, Luis
Silva-Caso, Wilmer
Costa, Luis E.
Weilg, Pablo
Alvitrez-Arana, Juan
Bazán-Mayra, Jorge
del Valle-Mendoza, Juana
Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title_full Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title_fullStr Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title_full_unstemmed Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title_short Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru
title_sort frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern peru
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069864/
https://www.ncbi.nlm.nih.gov/pubmed/30064521
http://dx.doi.org/10.1186/s13104-018-3644-7
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