High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway

BACKGROUND: Colorectal cancer (CRC) is a commonly diagnosed digestive malignancy worldwide. Ras-related protein 1A (RAP1A) is a member of the Ras superfamily of small GTPases and has been recently identified as a novel oncoprotein in several human malignancies. However, its specific role in CRC rema...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liguo, Yan, Xuebing, Wu, Dapeng, Yang, Yi, Li, Mengcheng, Su, Yang, Yang, Wenchao, Shan, Zezhi, Gao, Yuping, Jin, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069867/
https://www.ncbi.nlm.nih.gov/pubmed/30064475
http://dx.doi.org/10.1186/s13046-018-0827-y

Ejemplares similares

Ejemplares similares