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DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity

SLE is a complex autoimmune disease that results from the interplay of genetics, epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism that regulates gene expression and tissue differentiation. Among all the epigenetic modifications, DNA methylation perturbations have b...

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Detalles Bibliográficos
Autores principales:	Lanata, Cristina M, Chung, Sharon A, Criswell, Lindsey A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069928/ https://www.ncbi.nlm.nih.gov/pubmed/30094041 http://dx.doi.org/10.1136/lupus-2018-000285

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