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Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report

BACKGROUND: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. CASE PRESENTATION: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyis...

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Autores principales: Skogmar, Sten, Tham, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069954/
https://www.ncbi.nlm.nih.gov/pubmed/30064365
http://dx.doi.org/10.1186/s12879-018-3264-9
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author Skogmar, Sten
Tham, Johan
author_facet Skogmar, Sten
Tham, Johan
author_sort Skogmar, Sten
collection PubMed
description BACKGROUND: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. CASE PRESENTATION: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. CONCLUSIONS: Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease.
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spelling pubmed-60699542018-08-06 Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report Skogmar, Sten Tham, Johan BMC Infect Dis Case Report BACKGROUND: Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. CASE PRESENTATION: A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. CONCLUSIONS: Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease. BioMed Central 2018-07-31 /pmc/articles/PMC6069954/ /pubmed/30064365 http://dx.doi.org/10.1186/s12879-018-3264-9 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Skogmar, Sten
Tham, Johan
Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_full Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_fullStr Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_full_unstemmed Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_short Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_sort severe diphtheria with neurologic and myocardial involvement in a swedish patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069954/
https://www.ncbi.nlm.nih.gov/pubmed/30064365
http://dx.doi.org/10.1186/s12879-018-3264-9
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