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Iodate induced toxic retinopathy: a case report

BACKGROUND: Iodine deficiency is a common preventable cause of intellectual and developmental disabilities. Iodine in the form of potassium iodate is added to the common salt under the National Iodine Deficiency Disorder Control Program in India. Overdose of iodate can lead to retinal toxicity. CASE...

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Autores principales: Venu Gopal Reddy, Y. C., Sharma, Anuj, Shetty, Adheesh P., Abdul Kader, Syed Mohideen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069986/
https://www.ncbi.nlm.nih.gov/pubmed/30083392
http://dx.doi.org/10.1186/s40942-018-0130-2
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author Venu Gopal Reddy, Y. C.
Sharma, Anuj
Shetty, Adheesh P.
Abdul Kader, Syed Mohideen
author_facet Venu Gopal Reddy, Y. C.
Sharma, Anuj
Shetty, Adheesh P.
Abdul Kader, Syed Mohideen
author_sort Venu Gopal Reddy, Y. C.
collection PubMed
description BACKGROUND: Iodine deficiency is a common preventable cause of intellectual and developmental disabilities. Iodine in the form of potassium iodate is added to the common salt under the National Iodine Deficiency Disorder Control Program in India. Overdose of iodate can lead to retinal toxicity. CASE PRESENTATION: We hereby present a case of a 34 year old male patient who presented to us 10 years following iodate ingestion. There was widespread outer retinal atrophy, foveal atrophy and sub-retinal fibrosis noted on fundus evaluation. The fundus fluorescein angiogram was suggestive of window defects while the scotopic electroretinogram showed diminished amplitude pointing towards a grave prognosis. CONCLUSIONS: Excessive ingestion of potassium iodate can lead to outer retinal atrophy due to its toxicity to the retinal pigment epithelium and photo-receptors. The degree of damage is dependent on the ingested dose.
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spelling pubmed-60699862018-08-06 Iodate induced toxic retinopathy: a case report Venu Gopal Reddy, Y. C. Sharma, Anuj Shetty, Adheesh P. Abdul Kader, Syed Mohideen Int J Retina Vitreous Case Report BACKGROUND: Iodine deficiency is a common preventable cause of intellectual and developmental disabilities. Iodine in the form of potassium iodate is added to the common salt under the National Iodine Deficiency Disorder Control Program in India. Overdose of iodate can lead to retinal toxicity. CASE PRESENTATION: We hereby present a case of a 34 year old male patient who presented to us 10 years following iodate ingestion. There was widespread outer retinal atrophy, foveal atrophy and sub-retinal fibrosis noted on fundus evaluation. The fundus fluorescein angiogram was suggestive of window defects while the scotopic electroretinogram showed diminished amplitude pointing towards a grave prognosis. CONCLUSIONS: Excessive ingestion of potassium iodate can lead to outer retinal atrophy due to its toxicity to the retinal pigment epithelium and photo-receptors. The degree of damage is dependent on the ingested dose. BioMed Central 2018-08-01 /pmc/articles/PMC6069986/ /pubmed/30083392 http://dx.doi.org/10.1186/s40942-018-0130-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Venu Gopal Reddy, Y. C.
Sharma, Anuj
Shetty, Adheesh P.
Abdul Kader, Syed Mohideen
Iodate induced toxic retinopathy: a case report
title Iodate induced toxic retinopathy: a case report
title_full Iodate induced toxic retinopathy: a case report
title_fullStr Iodate induced toxic retinopathy: a case report
title_full_unstemmed Iodate induced toxic retinopathy: a case report
title_short Iodate induced toxic retinopathy: a case report
title_sort iodate induced toxic retinopathy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069986/
https://www.ncbi.nlm.nih.gov/pubmed/30083392
http://dx.doi.org/10.1186/s40942-018-0130-2
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