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Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei

Retroviral protease inhibitors (RPIs) such as lopinavir (LP) and saquinavir (SQ) are active against Plasmodium parasites. However, the exact molecular target(s) for these RPIs in the Plasmodium parasites remains poorly understood. We hypothesised that LP and SQ suppress parasite growth through inhib...

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Detalles Bibliográficos
Autores principales:	Onchieku, Noah Machuki, Mogire, Reagan, Ndung'u, Loise, Mwitari, Peter, Kimani, Francis, Matoke-Muhia, Damaris, Kiboi, Daniel, Magoma, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070271/ https://www.ncbi.nlm.nih.gov/pubmed/30067811 http://dx.doi.org/10.1371/journal.pone.0201556

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