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A bimodal switch in global protein translation coupled to eIF4H relocalisation during advancing cell-cell transmission of herpes simplex virus

We used the bioorthogonal protein precursor, homopropargylglycine (HPG) and chemical ligation to fluorescent capture agents, to define spatiotemporal regulation of global translation during herpes simplex virus (HSV) cell-to-cell spread at single cell resolution. Translational activity was spatially...

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Detalles Bibliográficos
Autores principales: Teo, Catherine Su Hui, O’Hare, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070287/
https://www.ncbi.nlm.nih.gov/pubmed/30028874
http://dx.doi.org/10.1371/journal.ppat.1007196