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Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein analyses
FUS-DDIT3 belongs to the FET (FUS, EWSR1, and TAF15) family of fusion oncogenes, which collectively are considered to be key players in tumor development. Even though over 90% of all myxoid liposarcomas (MLS) have a FUS-DDIT3 gene fusion, there is limited understanding of the signaling pathways that...
Autores principales: | Svec, David, Dolatabadi, Soheila, Thomsen, Christer, Cordes, Nicole, Shannon, Mark, Fitzpatrick, Paul, Landberg, Göran, Åman, Pierre, Ståhlberg, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070472/ https://www.ncbi.nlm.nih.gov/pubmed/29588491 http://dx.doi.org/10.1038/s41374-018-0046-3 |
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