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Evolution of high pathogenicity of H5 avian influenza virus: haemagglutinin cleavage site selection of reverse-genetics mutants during passage in chickens

Low pathogenicity avian influenza viruses (LPAIVs) are generally asymptomatic in their natural avian hosts. LPAIVs can evolve into highly pathogenic forms, which can affect avian and human populations with devastating consequences. The switch to highly pathogenic avian influenza virus (HPAIV) from L...

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Detalles Bibliográficos
Autores principales:	Luczo, Jasmina M., Tachedjian, Mary, Harper, Jennifer A., Payne, Jean S., Butler, Jeffrey M., Sapats, Sandra I., Lowther, Suzanne L., Michalski, Wojtek P., Stambas, John, Bingham, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070550/ https://www.ncbi.nlm.nih.gov/pubmed/30068964 http://dx.doi.org/10.1038/s41598-018-29944-z

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