Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate i...

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Detalles Bibliográficos
Autores principales: Jang, Guehwan, Kim, Seong-Hee, Lee, Yoo Jin, Kim, Seungjoon, Lee, Du Sik, Lee, Kyoung-Ki, Lee, Changhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070590/
https://www.ncbi.nlm.nih.gov/pubmed/29695146
http://dx.doi.org/10.4142/jvs.2018.19.4.577
Descripción
Sumario:Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.

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