Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate i...

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Detalles Bibliográficos
Autores principales: Jang, Guehwan, Kim, Seong-Hee, Lee, Yoo Jin, Kim, Seungjoon, Lee, Du Sik, Lee, Kyoung-Ki, Lee, Changhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070590/
https://www.ncbi.nlm.nih.gov/pubmed/29695146
http://dx.doi.org/10.4142/jvs.2018.19.4.577
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author Jang, Guehwan
Kim, Seong-Hee
Lee, Yoo Jin
Kim, Seungjoon
Lee, Du Sik
Lee, Kyoung-Ki
Lee, Changhee
author_facet Jang, Guehwan
Kim, Seong-Hee
Lee, Yoo Jin
Kim, Seungjoon
Lee, Du Sik
Lee, Kyoung-Ki
Lee, Changhee
author_sort Jang, Guehwan
collection PubMed
description Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.
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spelling pubmed-60705902018-08-08 Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07 Jang, Guehwan Kim, Seong-Hee Lee, Yoo Jin Kim, Seungjoon Lee, Du Sik Lee, Kyoung-Ki Lee, Changhee J Vet Sci Short Communication Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages. The Korean Society of Veterinary Science 2018-07 2018-07-26 /pmc/articles/PMC6070590/ /pubmed/29695146 http://dx.doi.org/10.4142/jvs.2018.19.4.577 Text en © 2018 The Korean Society of Veterinary Science http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Jang, Guehwan
Kim, Seong-Hee
Lee, Yoo Jin
Kim, Seungjoon
Lee, Du Sik
Lee, Kyoung-Ki
Lee, Changhee
Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title_full Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title_fullStr Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title_full_unstemmed Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title_short Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
title_sort isolation and characterization of korean porcine deltacoronavirus strain knu16-07
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070590/
https://www.ncbi.nlm.nih.gov/pubmed/29695146
http://dx.doi.org/10.4142/jvs.2018.19.4.577
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