Interleukin (IL)-2 Is a Key Regulator of T Helper 1 and T Helper 2 Cytokine Expression in Fish: Functional Characterization of Two Divergent IL2 Paralogs in Salmonids

Mammalian interleukin (IL)-2 is a cytokine centrally involved in the differentiation and survival of CD4+ T helper subsets and CD4+ T regulatory cells and in activation of cytotoxic effector lymphocytes. In bony fish, IL2 orthologs have been identified with an additional divergent IL2-Like gene on t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tiehui, Hu, Yehfang, Wangkahart, Eakapol, Liu, Fuguo, Wang, Alex, Zahran, Eman, Maisey, Kevin R., Liu, Min, Xu, Qiaoqing, Imarai, Mónica, Secombes, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070626/
https://www.ncbi.nlm.nih.gov/pubmed/30093902
http://dx.doi.org/10.3389/fimmu.2018.01683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070626/
https://www.ncbi.nlm.nih.gov/pubmed/30093902
http://dx.doi.org/10.3389/fimmu.2018.01683

Ejemplares similares