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Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population

The repurposing of the CRISPR/Cas microbial adaptive immune system for gene editing has resulted in an exponential rise in new technologies and promising approaches for treating numerous human diseases. While some of the approaches being currently developed involve ex vivo editing by CRISPR/Cas9, ma...

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Detalles Bibliográficos
Autores principales: Simhadri, Vijaya L., McGill, Joseph, McMahon, Shane, Wang, Junxia, Jiang, Haiyan, Sauna, Zuben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070699/
https://www.ncbi.nlm.nih.gov/pubmed/30073181
http://dx.doi.org/10.1016/j.omtm.2018.06.006