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Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population
The repurposing of the CRISPR/Cas microbial adaptive immune system for gene editing has resulted in an exponential rise in new technologies and promising approaches for treating numerous human diseases. While some of the approaches being currently developed involve ex vivo editing by CRISPR/Cas9, ma...
Autores principales: | Simhadri, Vijaya L., McGill, Joseph, McMahon, Shane, Wang, Junxia, Jiang, Haiyan, Sauna, Zuben E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070699/ https://www.ncbi.nlm.nih.gov/pubmed/30073181 http://dx.doi.org/10.1016/j.omtm.2018.06.006 |
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