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Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia

A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to hae...

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Autores principales: Foster, Mike N., Carr, Anitra C., Antony, Alina, Peng, Selene, Fitzpatrick, Mike G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070822/
https://www.ncbi.nlm.nih.gov/pubmed/30012948
http://dx.doi.org/10.3390/antiox7070092
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author Foster, Mike N.
Carr, Anitra C.
Antony, Alina
Peng, Selene
Fitzpatrick, Mike G.
author_facet Foster, Mike N.
Carr, Anitra C.
Antony, Alina
Peng, Selene
Fitzpatrick, Mike G.
author_sort Foster, Mike N.
collection PubMed
description A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient’s blood indices with platelet cell counts increasing from 25 × 10(9)/L to 196 × 10(9)/L and white blood cell counts increasing from 0.29 × 10(9)/L to 4.0 × 10(9)/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient’s health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML.
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spelling pubmed-60708222018-08-09 Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia Foster, Mike N. Carr, Anitra C. Antony, Alina Peng, Selene Fitzpatrick, Mike G. Antioxidants (Basel) Case Report A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient’s blood indices with platelet cell counts increasing from 25 × 10(9)/L to 196 × 10(9)/L and white blood cell counts increasing from 0.29 × 10(9)/L to 4.0 × 10(9)/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient’s health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML. MDPI 2018-07-16 /pmc/articles/PMC6070822/ /pubmed/30012948 http://dx.doi.org/10.3390/antiox7070092 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Foster, Mike N.
Carr, Anitra C.
Antony, Alina
Peng, Selene
Fitzpatrick, Mike G.
Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_full Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_fullStr Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_full_unstemmed Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_short Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia
title_sort intravenous vitamin c administration improved blood cell counts and health-related quality of life of patient with history of relapsed acute myeloid leukaemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070822/
https://www.ncbi.nlm.nih.gov/pubmed/30012948
http://dx.doi.org/10.3390/antiox7070092
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