Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases

BACKGROUND: A significant subset of prostate cancer (PC) patients with a castration-resistant form of the disease (CRPC) show primary resistance to androgen receptor (AR)-targeting drugs developed against CRPC. As one explanation could be the expression of constitutively active androgen receptor spl...

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Detalles Bibliográficos
Autores principales: Kallio, Heini M. L., Hieta, Reija, Latonen, Leena, Brofeldt, Anniina, Annala, Matti, Kivinummi, Kati, Tammela, Teuvo L., Nykter, Matti, Isaacs, William B., Lilja, Hans G., Bova, G. Steven, Visakorpi, Tapio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070921/
https://www.ncbi.nlm.nih.gov/pubmed/29988112
http://dx.doi.org/10.1038/s41416-018-0172-0

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