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Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake
Recent data have demonstrated that the hypothalamic GRP78/BiP (glucose regulated protein 78 kDa/binding immunoglobulin protein) modulates brown adipose tissue (BAT) thermogenesis by acting downstream on AMP-activated protein kinase (AMPK). Herein, we aimed to investigate whether genetic over-express...
Autores principales: | Liñares-Pose, Laura, Rial-Pensado, Eva, Estévez-Salguero, Ánxela, Milbank, Edward, González-García, Ismael, Rodríguez, Claudia, Seoane-Collazo, Patricia, Martinez-Sánchez, Noelia, Nogueiras, Rubén, Prieto, Dolores, Diéguez, Carlos, Contreras, Cristina, López, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070933/ https://www.ncbi.nlm.nih.gov/pubmed/30018241 http://dx.doi.org/10.3390/genes9070357 |
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