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Complexation of the Mycotoxin Cyclopiazonic Acid with Lanthanides Yields Luminescent Products
Cycopiazonic acid (CPA) is a neurotoxin that acts through inhibition of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA). CPA blocks the calcium access channel of the enzyme. The inhibition may involve the binding of CPA with a divalent cation such as Mg(2+). The potential for CPA to act as a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071049/ https://www.ncbi.nlm.nih.gov/pubmed/29996475 http://dx.doi.org/10.3390/toxins10070285 |