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Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues
Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge regarding the structured assessment and psychometric evaluation of clinical p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071094/ https://www.ncbi.nlm.nih.gov/pubmed/30011896 http://dx.doi.org/10.3390/brainsci8070133 |
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author | Bonaccorso, Stefania Metastasio, Antonio Ricciardi, Angelo Stewart, Neil Jamal, Leila Rujully, Naasir-Ud-Dinn Theleritis, Christos Ferracuti, Stefano Ducci, Giuseppe Schifano, Fabrizio |
author_facet | Bonaccorso, Stefania Metastasio, Antonio Ricciardi, Angelo Stewart, Neil Jamal, Leila Rujully, Naasir-Ud-Dinn Theleritis, Christos Ferracuti, Stefano Ducci, Giuseppe Schifano, Fabrizio |
author_sort | Bonaccorso, Stefania |
collection | PubMed |
description | Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge regarding the structured assessment and psychometric evaluation of clinical presentations, analytical toxicology and clinical management plans of patients presenting with psychosis and SCRAs misuse. Methods: We gathered information regarding the clinical presentations, toxicology and care plans of patients with psychosis and SCRAs misuse admitted to inpatients services. Clinical presentations were assessed using the PANSS scale. Vital signs data were collected using the National Early Warning Signs tool. Analytic chemistry data were collected using urine drug screening tests for traditional psychoactive substances and NPS. Results: We described the clinical presentation and management plan of four patients with psychosis and misuse of SCRAs. Conclusion: The formulation of an informed clinical management plan requires a structured assessment, identification of the index NPS, pharmacological interventions, increases in nursing observations, changes to leave status and monitoring of the vital signs. The objective from using these interventions is to maintain stable physical health whilst rapidly improving the altered mental state. |
format | Online Article Text |
id | pubmed-6071094 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60710942018-08-09 Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues Bonaccorso, Stefania Metastasio, Antonio Ricciardi, Angelo Stewart, Neil Jamal, Leila Rujully, Naasir-Ud-Dinn Theleritis, Christos Ferracuti, Stefano Ducci, Giuseppe Schifano, Fabrizio Brain Sci Article Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge regarding the structured assessment and psychometric evaluation of clinical presentations, analytical toxicology and clinical management plans of patients presenting with psychosis and SCRAs misuse. Methods: We gathered information regarding the clinical presentations, toxicology and care plans of patients with psychosis and SCRAs misuse admitted to inpatients services. Clinical presentations were assessed using the PANSS scale. Vital signs data were collected using the National Early Warning Signs tool. Analytic chemistry data were collected using urine drug screening tests for traditional psychoactive substances and NPS. Results: We described the clinical presentation and management plan of four patients with psychosis and misuse of SCRAs. Conclusion: The formulation of an informed clinical management plan requires a structured assessment, identification of the index NPS, pharmacological interventions, increases in nursing observations, changes to leave status and monitoring of the vital signs. The objective from using these interventions is to maintain stable physical health whilst rapidly improving the altered mental state. MDPI 2018-07-14 /pmc/articles/PMC6071094/ /pubmed/30011896 http://dx.doi.org/10.3390/brainsci8070133 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bonaccorso, Stefania Metastasio, Antonio Ricciardi, Angelo Stewart, Neil Jamal, Leila Rujully, Naasir-Ud-Dinn Theleritis, Christos Ferracuti, Stefano Ducci, Giuseppe Schifano, Fabrizio Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title | Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title_full | Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title_fullStr | Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title_full_unstemmed | Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title_short | Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues |
title_sort | synthetic cannabinoid use in a case series of patients with psychosis presenting to acute psychiatric settings: clinical presentation and management issues |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071094/ https://www.ncbi.nlm.nih.gov/pubmed/30011896 http://dx.doi.org/10.3390/brainsci8070133 |
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