Conserved Active-Site Residues Associated with OAS Enzyme Activity and Ubiquitin-Like Domains Are Not Required for the Antiviral Activity of goOASL Protein against Avian Tembusu Virus

Interferon (IFN)-induced 2′-5′-oligoadenylate synthetase (OAS) proteins exhibit an extensive and efficient antiviral effect against flavivirus infection in mammals and birds. Only the 2′-5′-oligoadenylate synthetase-like (OASL) gene has been identified thus far in birds, except for ostrich, which ha...

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Detalles Bibliográficos
Autores principales: Chen, Shun, Yang, Chao, Zhang, Jinyue, Wu, Zhen, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Yang, Qiao, Wu, Ying, Zhao, Xinxin, Zhang, Shaqiu, Liu, Yunya, Zhang, Ling, Yu, Yanling, You, Yu, Cheng, Anchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071104/
https://www.ncbi.nlm.nih.gov/pubmed/30011971
http://dx.doi.org/10.3390/v10070371

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