Cargando…
Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products
Natural products originating from marine and plant materials are a rich source of chemical diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we screened 257 pure compounds from a marine natural product library and identified 4 (psammaplin A, aplysiatoxin, deb...
Autores principales: | Richard, Khumoekae, Williams, David E., de Silva, E. Dilip, Brockman, Mark A., Brumme, Zabrina L., Andersen, Raymond J., Tietjen, Ian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071113/ https://www.ncbi.nlm.nih.gov/pubmed/29954099 http://dx.doi.org/10.3390/v10070348 |
Ejemplares similares
-
Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening
por: Divsalar, Donya Naz, et al.
Publicado: (2020) -
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
por: Tietjen, Ian, et al.
Publicado: (2015) -
CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells
por: Horvath, Riley M., et al.
Publicado: (2023) -
Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs
por: Brockman, Mark A., et al.
Publicado: (2015) -
Naturally-arising amino acid polymorphisms of HIV-1 Nef that differentially modulate downregulation of HLA-A and HLA-B molecules
por: Mahiti, Macdonald, et al.
Publicado: (2013)