Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity

Botulinum neurotoxins (BoNTs) are highly successful protein therapeutics. Over 40 naturally occurring BoNTs have been described thus far and, of those, only 2 are commercially available for clinical use. Different members of the BoNT family present different biological properties but share a similar...

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Detalles Bibliográficos
Autores principales: Fonfria, Elena, Elliott, Mark, Beard, Matthew, Chaddock, John A., Krupp, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071219/
https://www.ncbi.nlm.nih.gov/pubmed/29973505
http://dx.doi.org/10.3390/toxins10070278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071219/
https://www.ncbi.nlm.nih.gov/pubmed/29973505
http://dx.doi.org/10.3390/toxins10070278

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