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Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity
Botulinum neurotoxins (BoNTs) are highly successful protein therapeutics. Over 40 naturally occurring BoNTs have been described thus far and, of those, only 2 are commercially available for clinical use. Different members of the BoNT family present different biological properties but share a similar...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071219/ https://www.ncbi.nlm.nih.gov/pubmed/29973505 http://dx.doi.org/10.3390/toxins10070278 |