Description of Genetic Variants in BRCA Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine

Gynecologic cancers are among the leading causes of death worldwide, ovarian cancer being the one with the highest mortality rate. Olaparib is a targeted therapy used in patients presenting mutations in BRCA1 and BRCA2 genes. The aim of this study was to describe BRCA1 and BRCA2 gene variants in Mex...

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Detalles Bibliográficos
Autores principales: Delgado-Balderas, Jesus Rolando, Garza-Rodriguez, Maria Lourdes, Gomez-Macias, Gabriela Sofia, Barboza-Quintana, Alvaro, Barboza-Quintana, Oralia, Cerda-Flores, Ricardo M., Miranda-Maldonado, Ivett, Vazquez-Garcia, Hugo Mauricio, Valdez-Chapa, Lezmes Dionicio, Antonio-Macedo, Mauro, Dean, Michael, Barrera-Saldaña, Hugo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071230/
https://www.ncbi.nlm.nih.gov/pubmed/29997359
http://dx.doi.org/10.3390/genes9070349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071230/
https://www.ncbi.nlm.nih.gov/pubmed/29997359
http://dx.doi.org/10.3390/genes9070349

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