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Description of Genetic Variants in BRCA Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine
Gynecologic cancers are among the leading causes of death worldwide, ovarian cancer being the one with the highest mortality rate. Olaparib is a targeted therapy used in patients presenting mutations in BRCA1 and BRCA2 genes. The aim of this study was to describe BRCA1 and BRCA2 gene variants in Mex...
Autores principales: | Delgado-Balderas, Jesus Rolando, Garza-Rodriguez, Maria Lourdes, Gomez-Macias, Gabriela Sofia, Barboza-Quintana, Alvaro, Barboza-Quintana, Oralia, Cerda-Flores, Ricardo M., Miranda-Maldonado, Ivett, Vazquez-Garcia, Hugo Mauricio, Valdez-Chapa, Lezmes Dionicio, Antonio-Macedo, Mauro, Dean, Michael, Barrera-Saldaña, Hugo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071230/ https://www.ncbi.nlm.nih.gov/pubmed/29997359 http://dx.doi.org/10.3390/genes9070349 |
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