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Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber

In this report, we designed and synthesized polyacrylonitrile/silver (PAN/AgNPs) nanofibers via an in-situ method to obtain a washable with high-dispersed silver nanoparticles membrane to form the hierarchically organized antibacterial mask to prevent the two-way effect of bacteria from person to en...

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Autores principales: Kharaghani, Davood, Khan, Muhammad Qamar, Shahzad, Amir, Inoue, Yuma, Yamamoto, Takayuki, Rozet, Selene, Tamada, Yasushi, Kim, Ick Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071278/
https://www.ncbi.nlm.nih.gov/pubmed/29941857
http://dx.doi.org/10.3390/nano8070461
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author Kharaghani, Davood
Khan, Muhammad Qamar
Shahzad, Amir
Inoue, Yuma
Yamamoto, Takayuki
Rozet, Selene
Tamada, Yasushi
Kim, Ick Soo
author_facet Kharaghani, Davood
Khan, Muhammad Qamar
Shahzad, Amir
Inoue, Yuma
Yamamoto, Takayuki
Rozet, Selene
Tamada, Yasushi
Kim, Ick Soo
author_sort Kharaghani, Davood
collection PubMed
description In this report, we designed and synthesized polyacrylonitrile/silver (PAN/AgNPs) nanofibers via an in-situ method to obtain a washable with high-dispersed silver nanoparticles membrane to form the hierarchically organized antibacterial mask to prevent the two-way effect of bacteria from person to environment and environment to person. For this objective, the electrospun PAN nanofibers were stabilized via the heating method. Different amounts of AgNPs were loaded into the PAN nanofibers by using silver nitrate and sodium hydroxide solutions. The basic results showed that AgNPs was homogenously loaded in PAN nanofiber matrixes. Furthermore, the release profile based on two-stage release theory showed that when the negligible amount of AgNPs was loaded into the nanofibers, the release significantly decreased, whereas antibacterial activity increased. The greatest potential antibacterial activity of the lowest amount of AgNPs showed controllable AgNPs release from PAN nanofibers that has a direct relationship with the washability and could promote the application of the produced product.
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spelling pubmed-60712782018-08-09 Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber Kharaghani, Davood Khan, Muhammad Qamar Shahzad, Amir Inoue, Yuma Yamamoto, Takayuki Rozet, Selene Tamada, Yasushi Kim, Ick Soo Nanomaterials (Basel) Article In this report, we designed and synthesized polyacrylonitrile/silver (PAN/AgNPs) nanofibers via an in-situ method to obtain a washable with high-dispersed silver nanoparticles membrane to form the hierarchically organized antibacterial mask to prevent the two-way effect of bacteria from person to environment and environment to person. For this objective, the electrospun PAN nanofibers were stabilized via the heating method. Different amounts of AgNPs were loaded into the PAN nanofibers by using silver nitrate and sodium hydroxide solutions. The basic results showed that AgNPs was homogenously loaded in PAN nanofiber matrixes. Furthermore, the release profile based on two-stage release theory showed that when the negligible amount of AgNPs was loaded into the nanofibers, the release significantly decreased, whereas antibacterial activity increased. The greatest potential antibacterial activity of the lowest amount of AgNPs showed controllable AgNPs release from PAN nanofibers that has a direct relationship with the washability and could promote the application of the produced product. MDPI 2018-06-25 /pmc/articles/PMC6071278/ /pubmed/29941857 http://dx.doi.org/10.3390/nano8070461 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kharaghani, Davood
Khan, Muhammad Qamar
Shahzad, Amir
Inoue, Yuma
Yamamoto, Takayuki
Rozet, Selene
Tamada, Yasushi
Kim, Ick Soo
Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title_full Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title_fullStr Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title_full_unstemmed Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title_short Preparation and In-Vitro Assessment of Hierarchal Organized Antibacterial Breath Mask Based on Polyacrylonitrile/Silver (PAN/AgNPs) Nanofiber
title_sort preparation and in-vitro assessment of hierarchal organized antibacterial breath mask based on polyacrylonitrile/silver (pan/agnps) nanofiber
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071278/
https://www.ncbi.nlm.nih.gov/pubmed/29941857
http://dx.doi.org/10.3390/nano8070461
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