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Chlamydial Plasmid-Encoded Protein pGP3 Inhibits Development of Psoriasis-Like Lesions in Mice

BACKGROUND: The anti-microbial protein cathelicidin LL-37 plays an important role in the pathogenesis of psoriasis by inducing inflammation. Our previous study showed that the chlamydial plasmid-encoded protein pGP3 forms a stable complex with LL-37 to neutralize its pro-inflammatory activity. Here,...

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Detalles Bibliográficos
Autores principales: Hou, Shuping, Xu, Rong, Zhu, Congzhong, Shan, Shijun, Han, Long, Wang, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071496/
https://www.ncbi.nlm.nih.gov/pubmed/30043770
http://dx.doi.org/10.12659/MSM.910472