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Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli

Ruminococcin A (RumA) is a lanthipeptide with high activity against pathogenic clostridia and is naturally produced by the strict anaerobic bacterium Ruminococcus gnavus E1, isolated from human intestine. Cultivating R. gnavus E1 is challenging, limiting high-quality production, further biotechnolog...

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Detalles Bibliográficos
Autores principales:	Ongey, Elvis L., Giessmann, Robert T., Fons, Michel, Rappsilber, Juri, Adrian, Lorenz, Neubauer, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071512/ https://www.ncbi.nlm.nih.gov/pubmed/30093894 http://dx.doi.org/10.3389/fmicb.2018.01688

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