HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling

Human tumorous imaginal disc (Tid1), a DnaJ co-chaperone protein, is classified as a tumor suppressor. Previously, we demonstrated that Tid1 reduces head and neck squamous cell carcinoma (HNSCC) malignancy. However, the molecular details of Tid1-mediated anti-metastasis remain elusive. Methods: We u...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Syuan, Chang, Ching-Wen, Tsay, Yeou-Guang, Huang, Liu-Ying, Wu, Yi-Chen, Cheng, Li-Hao, Yang, Cheng-Chieh, Wu, Cheng-Hsien, Teo, Wan-Huai, Hung, Kai-Feng, Huang, Chih-Yang, Lee, Te-Chang, Lo, Jeng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071538/
https://www.ncbi.nlm.nih.gov/pubmed/30083263
http://dx.doi.org/10.7150/thno.25784

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