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Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Tumors with anaplastic lymphoma kinase (ALK) fusion rearrangements, including non-small-cell lung cancer and anaplastic large cell lymphoma, are highly sensitive to ALK tyrosine kinase inhibitors (TKIs), underscoring the notion that such cancers are addicted to ALK activity. Although mutations in AL...

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Detalles Bibliográficos
Autores principales:	Guan, Jikui, Fransson, Susanne, Siaw, Joachim Tetteh, Treis, Diana, Van den Eynden, Jimmy, Chand, Damini, Umapathy, Ganesh, Ruuth, Kristina, Svenberg, Petter, Wessman, Sandra, Shamikh, Alia, Jacobsson, Hans, Gordon, Lena, Stenman, Jakob, Svensson, Pär-Johan, Hansson, Magnus, Larsson, Erik, Martinsson, Tommy, Palmer, Ruth H., Kogner, Per, Hallberg, Bengt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071567/ https://www.ncbi.nlm.nih.gov/pubmed/29907598 http://dx.doi.org/10.1101/mcs.a002550

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