Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System

Paired-homeodomain transcription factor 4 (PAX4) gene encodes a transcription factor which plays an important role in the generation, differentiation, development, and survival of insulin-producing β-cells during mammalian pancreas development. PAX4 is a key diabetes mellitus (DM) susceptibility gen...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Wang, Yong, Song, Yuning, Deng, Jichao, Chen, Mao, Ouyang, Hongsheng, Lai, Liangxue, Li, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071587/
https://www.ncbi.nlm.nih.gov/pubmed/29950431
http://dx.doi.org/10.1534/g3.118.300448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071587/
https://www.ncbi.nlm.nih.gov/pubmed/29950431
http://dx.doi.org/10.1534/g3.118.300448

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