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Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease Etiology
Idiopathic scoliosis (IS) is a structural lateral spinal curvature of ≥10° that affects up to 3% of otherwise healthy children and can lead to life-long problems in severe cases. It is well-established that IS is a genetic disorder. Previous studies have identified genes that may contribute to the I...
Autores principales: | Baschal, Erin E., Terhune, Elizabeth A., Wethey, Cambria I., Baschal, Robin M., Robinson, Kandice D., Cuevas, Melissa T., Pradhan, Shreyash, Sutphin, Brittan S., Taylor, Matthew R. G., Gowan, Katherine, Pearson, Chad G., Niswander, Lee A., Jones, Kenneth L., Miller, Nancy H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071588/ https://www.ncbi.nlm.nih.gov/pubmed/29930198 http://dx.doi.org/10.1534/g3.118.200290 |
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