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On the Relationship Between High-Order Linkage Disequilibrium and Epistasis
A plausible explanation for statistical epistasis revealed in genome wide association analyses is the presence of high order linkage disequilibrium (LD) between the genotyped markers tested for interactions and unobserved functional polymorphisms. Based on findings in experimental data, it has been...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071592/ https://www.ncbi.nlm.nih.gov/pubmed/29945968 http://dx.doi.org/10.1534/g3.118.200513 |