Cargando…

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate

Diphosphoinositol phosphates (PP-InsPs) are inositol phosphates (InsPs) that contain PP (diphosphate) groups. Converting a phosphate group in an InsP into a diphosphate has been reported to enhance affinity for some binding proteins. We synthesised 1-PP-Ins(4,5)P(2), the first diphosphate analogue o...

Descripción completa

Detalles Bibliográficos
Autores principales: Riley, Andrew M., Unterlass, Judith E., Konieczny, Vera, Taylor, Colin W., Helleday, Thomas, Potter, Barry V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071853/
https://www.ncbi.nlm.nih.gov/pubmed/30079174
http://dx.doi.org/10.1039/c8md00149a