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The TCR is randomly distributed on the plasma membrane of resting antigen-experienced T cells
It is the main function of T cells to identify harmful antigens as quickly and precisely as possible. Super-resolution microscopy data has indicated that global clustering of the T cell receptor (TCR) occurs prior to T cell activation. Such pre-activation clustering has been interpreted as represent...
Autores principales: | Rossboth, Benedikt, Arnold, Andreas M., Ta, Haisen, Platzer, René, Kellner, Florian, Huppa, Johannes B., Brameshuber, Mario, Baumgart, Florian, Schütz, Gerhard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071872/ https://www.ncbi.nlm.nih.gov/pubmed/30013143 http://dx.doi.org/10.1038/s41590-018-0162-7 |
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