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Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides

A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides. The required building blocks were conveniently accessible from cysteine and could be applied in a solid phase peptide synthesis protoc...

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Detalles Bibliográficos
Autores principales: Silva Nigenda, Ezequiel, Postma, Tobias M., Hezwani, Mohammed, Pirvan, Alin, Gannon, Susan, Smith, Carol-Anne, Riehle, Mathis, Liskamp, Rob M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071932/
https://www.ncbi.nlm.nih.gov/pubmed/30108987
http://dx.doi.org/10.1039/c8md00113h

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