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Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)

Breast cancer is the leading cause of cancer related deaths in women worldwide and is classified into subtypes based on the cancer’s receptor status. Of these subtypes, those expressing the human epidermal growth factor receptor 2 (HER2) receptor were traditionally associated with poor prognosis. Se...

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Detalles Bibliográficos
Autores principales: Coté, Damien, Eustace, Alex, Toomey, Sinead, Cremona, Mattia, Milewska, Malgorzata, Furney, Simon, Carr, Aoife, Fay, Joanna, Kay, Elaine, Kennedy, Susan, Crown, John, Hennessy, Bryan, Madden, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071997/
https://www.ncbi.nlm.nih.gov/pubmed/30071039
http://dx.doi.org/10.1371/journal.pone.0200996