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Pioglitazone restores the homocysteine-impaired function of endothelial progenitor cells via the inhibition of the protein kinase C/NADPH oxidase pathway

Homocysteine (Hcy) has been shown to impair the migratory and adhesive activity of endothelial progenitor cells (EPCs). As a peroxisome proliferator-activated receptor γ agonist, pioglitazone (PIO) has been predicted to regulate angiogenesis, and cell adhesion, migration and survival. The aim of the...

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Detalles Bibliográficos
Autores principales: Zhu, Junhui, Zhao, Yanbo, Yu, Lu, Wang, Meihui, Li, Qinfeng, Xu, Shengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072150/
https://www.ncbi.nlm.nih.gov/pubmed/29901193
http://dx.doi.org/10.3892/mmr.2018.9154