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Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome-mediated IL-1β secretion via c-Jun N-terminal kinase activation and cell apoptosis during diabetic nephropathy

Diabetic nephropathy (DN) is a serious complication of diabetes and can cause an increased mortality risk. It was previously reported that NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in the pathogenesis of diabetes. However, the underlying mechanism is not clearly understoo...

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Detalles Bibliográficos
Autores principales:	Qiao, Yingchun, Tian, Xixi, Men, Li, Li, Shengyu, Chen, Yufeng, Xue, Meiting, Hu, Yahui, Zhou, Pengfei, Long, Guangfeng, Shi, Yue, Liu, Ruiqing, Liu, Yunde, Qi, Zhi, Cui, Yujie, Shen, Yanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072182/ https://www.ncbi.nlm.nih.gov/pubmed/29901140 http://dx.doi.org/10.3892/mmr.2018.9164

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