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SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF-κB pathway in mouse kupffer cells

Sirtuin 1 (SIRT1) is an NAD(+)-dependent deacetylase, and a critical regulator in various metabolic processes, such as non-alcoholic fatty liver disease (NAFLD). The present study aimed to investigate whether activating SIRT1 could modulate the CD36 and nuclear factor (NF)-κB pathways to protect aga...

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Detalles Bibliográficos
Autores principales:	Niu, Bailin, He, Kun, Li, Peizhi, Gong, Jianping, Zhu, Xiwen, Ye, Shangmin, Ou, Zhibing, Ren, Guosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072223/ https://www.ncbi.nlm.nih.gov/pubmed/29845302 http://dx.doi.org/10.3892/mmr.2018.9088

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