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Genetic characterization of the HIV-1 reservoir after Vacc-4x and romidepsin therapy in HIV-1-infected individuals

OBJECTIVE: Therapeutic HIV-1 immunization followed by latency reversal has been suggested as a strategy to eradicate HIV-1. Here we investigate the phylogenetic composition of the HIV-1 regions targeted by the therapeutic HIV-1 peptide vaccine Vacc-4x in participants in a clinical trial. DESIGN: Sev...

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Detalles Bibliográficos
Autores principales: Winckelmann, Anni, Morcilla, Vincent, Shao, Wei, Schleimann, Mariane H., Hojen, Jesper F., Schlub, Timothy E., Benton, Paul W., Østergaard, Lars, Søgaard, Ole S., Tolstrup, Martin, Palmer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072375/
https://www.ncbi.nlm.nih.gov/pubmed/29762162
http://dx.doi.org/10.1097/QAD.0000000000001861