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Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids

Acetaminophen (APAP) is possibly the most widely used medication globally and yet little is known of its molecular effects at therapeutic doses. Using a novel approach, we have analysed the redox proteome of the hepatocellular cell line HepG2/C3A treated with therapeutic doses of APAP and quantitate...

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Detalles Bibliográficos
Autores principales: Wojdyla, Katarzyna, Wrzesinski, Krzysztof, Williamson, James, Fey, Stephen J., Rogowska-Wrzesinska, Adelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072433/
https://www.ncbi.nlm.nih.gov/pubmed/30090399
http://dx.doi.org/10.1039/c5tx00469a

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