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Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids
Acetaminophen (APAP) is possibly the most widely used medication globally and yet little is known of its molecular effects at therapeutic doses. Using a novel approach, we have analysed the redox proteome of the hepatocellular cell line HepG2/C3A treated with therapeutic doses of APAP and quantitate...
Autores principales: | Wojdyla, Katarzyna, Wrzesinski, Krzysztof, Williamson, James, Fey, Stephen J., Rogowska-Wrzesinska, Adelina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072433/ https://www.ncbi.nlm.nih.gov/pubmed/30090399 http://dx.doi.org/10.1039/c5tx00469a |
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