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High Throughput Identification of Non-Coding Functional SNPs via Type IIS Enzyme Restriction

Genome wide association studies have identified many disease-associated non-coding single nucleotide polymorphisms, but cannot distinguish functional SNPs (fSNPs) from others that reside incidentally within risk loci. To address this challenge, we developed an unbiased high-throughput screen that em...

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Detalles Bibliográficos
Autores principales:	Li, Gang, Martínez-Bonet, Marta, Wu, Di, Yang, Yu, Cui, Jing, Nguyen, Hung N., Cunin, Pierre, Levescot, Anaïs, Bai, Ming, Westra, Harm-Jan, Okada, Yukinori, Brenner, Michael B., Raychaudhuri, Soumya, Hendrickson, Eric A., Maas, Richard L., Nigrovic, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072570/ https://www.ncbi.nlm.nih.gov/pubmed/30013183 http://dx.doi.org/10.1038/s41588-018-0159-z

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