Krebs Cycle-Deficient Hereditary Cancer Syndromes are Defined by Homologous Recombination DNA Repair Defects

The hereditary cancer syndromes, Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) and Succinate Dehydrogenase-related Hereditary Paraganglioma and Pheochromocytoma (SDH PGL/PCC), are linked to germline loss-of-function mutations in the fumarate hydratase (FH) and succinate dehydrogenase (SDH)...

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Detalles Bibliográficos
Autores principales: Sulkowski, Parker L., Sundaram, Ranjini K., Oeck, Sebastian, Corso, Christopher D., Liu, Yanfeng, Noorbakhsh, Seth, Niger, Monica, Boeke, Marta, Ueno, Daiki, Kalathil, Aravind Nambiar, Bao, Xun, Li, Jing, Shuch, Brian, Bindra, Ranjit S., Glazer, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072579/
https://www.ncbi.nlm.nih.gov/pubmed/30013182
http://dx.doi.org/10.1038/s41588-018-0170-4

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