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Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids
Human pluripotent stem cell (hPSC)-derived intestinal organoids (hIOs) form 3D structures organized into crypt and villus domains, making them an excellent in vitro model system for studying human intestinal development and disease. However, hPSC-derived hIOs still require in vivo maturation to full...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072745/ https://www.ncbi.nlm.nih.gov/pubmed/30072687 http://dx.doi.org/10.1038/s41467-018-05450-8 |