Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer

ESR1 mutations were recently found to be an important mechanism of endocrine resistance in ER-positive (ER + ) metastatic breast cancer. To determine the clinicopathological features driving the emergence of the ESR1 mutations we studied plasma cfDNA and detailed clinical data collected from patient...

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Detalles Bibliográficos
Autores principales: Kuang, Yanan, Siddiqui, Bilal, Hu, Jiani, Pun, Matthew, Cornwell, MacIntosh, Buchwalter, Gilles, Hughes, Melissa E., Wagle, Nikhil, Kirschmeier, Paul, Jänne, Pasi A., Paweletz, Cloud P., Lin, Nancy U., Krop, Ian E., Barry, William T., Winer, Eric P., Brown, Myles, Jeselsohn, Rinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072793/
https://www.ncbi.nlm.nih.gov/pubmed/30083595
http://dx.doi.org/10.1038/s41523-018-0075-5

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