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Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses

Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell membrane repair mechanisms have been identified: i...

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Detalles Bibliográficos
Autores principales:	Köffel, René, Wolfmeier, Heidi, Larpin, Yu, Besançon, Hervé, Schoenauer, Roman, Babiychuk, Viktoria S., Drücker, Patrick, Pabst, Thomas, Mitchell, Timothy J., Babiychuk, Eduard B., Draeger, Annette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072879/ https://www.ncbi.nlm.nih.gov/pubmed/30100903 http://dx.doi.org/10.3389/fimmu.2018.01688

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