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Optimized alamarBlue assay protocol for drug dose-response determination of 3D tumor spheroids

The assessment of drug-dose responses is vital for the prediction of unwanted toxicological effects in modern medicine. Three-dimensional (3D) cell cultures techniques can provide in vivo-like spheroids and microtissues that resemble natural tumor function. However, formation of necrotic core and di...

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Detalles Bibliográficos
Autores principales:	Eilenberger, Christoph, Kratz, Sebastian Rudi Adam, Rothbauer, Mario, Ehmoser, Eva-Kathrin, Ertl, Peter, Küpcü, Seta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072978/ https://www.ncbi.nlm.nih.gov/pubmed/30094205 http://dx.doi.org/10.1016/j.mex.2018.07.011

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