Single-crystal X-ray diffraction study of a host–guest system comprising monofunctionalized-hydroxy pillar[5]arene and 1-octa­namine

Co-crystallization of a monofunctionalized hy­droxy pillar[5]arene with 1-octa­namine resulted in the formation of an inclusion complex where the alkyl chain is threaded in the macrocycle cavity, namely 1,2,3,4-(1,4-dimeth­oxy)-5-(1-hy­droxy-4-meth­oxy)-pillar[5]arene–1-octa­namine–water (1/1/1), C(44)H(48)O(10)·C(8)H(19)N·H(2)O. The guest compound is stabilized inside the cavity by hydrogen-bonding and C—H⋯π inter­actions. The water mol­ecule in the asymmetric unit mediates the formation of a supra­molecular dimer by hydrogen-bonding inter­actions. These functionalized-pillararene hosts expand the possibility of exploring more supra­molecular inter­actions with various guest species.